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1. act of irritating; state of being irritated; something which annoys or aggravates; inflammation, excessive sensitivity (Medicine). irritation\ir`ri*ta"tion\ , n. [l. irritatio: cf. f. irritation.]. 2. the act of irritating, or exciting, or the state of being irritated; excitement; stimulation, usually of an undue and uncomfortable kind; especially, excitement of anger or passion; provocation; annoyance; anger. the whole body of the arts and sciences composes one vast machinery for the irritation and development of the human intellect. 3. (physiol.) the act of exciting, or the condition of being excited to action, by stimulation; -- as, the condition of an organ of sense, when its nerve is affected by some external body; esp., the act of exciting muscle fibers to contraction, by artificial stimulation; as, the irritation of a motor nerve by electricity; also, the condition of a muscle and nerve, under such stimulation. 4. (med.) a condition of morbid excitability or oversensitiveness of an organ or part of the body; a state in which the application of ordinary stimuli produces pain or excessive or vitiated action.irritation n. 5. the psychological state of being irritated or annoyed [syn: annoyance, vexation]. 6. a sudden outburst of anger; "his temper sparked like damp firewood" [syn: pique, temper]. 7. an uncomfortable feeling in some part of the body [syn: discomfort, soreness]. 8. unfriendly behavior that aggravates or irritates someone [syn: aggravation, provocation]. 9. the act of troubling or annoying someone [syn: annoyance, annoying, vexation]. 10. The act of irritating, or exciting, or the state of being irritated; excitement; stimulation, usually of an undue and uncomfortable kind; especially, excitement of anger or passion; provocation; annoyance; anger. 11. The act of exciting, or the condition of being excited to action, by stimulation; as, the condition of an organ of sense, when its nerve is affected by some external body; esp., the act of exciting muscle fibers to contraction, by artificial stimulation; as, the irritation of a motor nerve by electricity; also, the condition of a muscle and nerve, under such stimulation. 12. A condition of morbid excitability or oversensitiveness of an organ or part of the body; a state in which the application of ordinary stimuli produces pain or excessive or vitiated action. the psychological state of being irritated or annoyed abnormal sensitivity to stimulation; "any food produced irritation of the stomach". 13. 1. Irritation is a feeling of annoyance, especially when something is happening that you cannot easily stop or control. He tried not to let his irritation show as he blinked in the glare of the television lights. = annoyance. 14. An irritation is something that keeps annoying you. Don't allow a minor irritation in the workplace to mar your ambitions = annoyance. 15. Irritation in a part of your body is a feeling of slight pain and discomfort there. These oils may cause irritation to sensitive skins.
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